It is not known if ONUREG® is safe and effective in children under 18 years of age.
What is AML
(acute myeloid leukemia)?
AML is a blood cancer that starts in the bone marrow
The bone marrow is a soft tissue found within the bones
Bone marrow typically produces platelets (which help with blood clotting), red blood cells (which transport oxygen throughout the body), and white blood cells (which help fight infection)
In most cases, AML can quickly move from the bone marrow into the blood and can sometimes spread to other parts of the body
In AML, the bone marrow makes abnormal blood cells
Normally, the bone marrow makes immature cells that go on to become mature blood cells
In AML, blood cells don’t form properly in the bone marrow and young, immature cells, called myeloblasts, or blasts for short, are produced instead. Blasts are unable to fight infections the way healthy blood cells can
As the bone marrow produces more and more blasts, there is no room for the production of normal platelets, red blood cells, and white blood cells. When there are too many blasts and not enough healthy cells, the symptoms of AML begin to occur
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Treatment for someone with AML typically starts as soon as possible
Acute means that this disease can get worse quickly if left untreated.
Depending on factors like age or the type of AML, a person with AML may receive a few treatments before they start to feel better.
A main goal of treatment is to eliminate the blasts in the blood and bone marrow
The first phase of treatment, called induction therapy, is usually the strongest against blasts.
The goal of induction therapy is to achieve complete remission. Complete remission, or remission for short, describes the absence of signs and symptoms of AML.*
Continued treatment for AML
Your healthcare team will decide if treatment after remission is necessary
Goals of treatment may include preventing AML from returning and helping patients live longer.*
Post-remission treatment options include:
- Additional chemotherapy: Consists of similar drugs used during induction, however, at different doses. This treatment is also known as consolidation therapy
- Bone marrow transplant: Involves transferring healthy stem cells from a donor to a person with AML. This treatment is also known as a stem cell transplant or a hematopoietic stem cell transplant
Potential treatment journey for people with AML
*NCCN makes no warranties of any kind whatsoever regarding their content, use or application and disclaims any responsibility for their application or use in any way.